The Curbsiders Internal Medicine Podcast

#474 Resistant Hypertension the Next Frontier

Mon, 10 Mar 2025

Treat Hypertension Like No Doctor Has Ever Treated Hypertension Before

Treating hypertension never gets boring. Learn about emerging therapies and how to continue to tackle this common diagnosis like a pro. Dr. Jordy Cohen (@jordybc.bsky.social) leads us through her approach to keeping the BP where it should be (University of Pennsylvania).

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Show Segments

00:00 Introduction and Current Interests

01:55 Understanding Hypertension

11:59 Blood Pressure Measurement Techniques

19:58 Treatment Goals and Guidelines for Hypertension

30:02 Managing Resistant Hypertension and New Treatments

36:00 Exploring GLP-1 Agonists and Blood Pressure Benefits

39:06 Aldosterone Synthase Inhibitors: A New Hope

42:00 Innovative Approaches: Small Interfering RNAs in Hypertension

47:06 Renal Denervation: A Controversial Procedure

55:01 Understanding Resistant Hypertension and Testing Protocols

Credits

Writer and Producer: Deborah Gorth MD, PhD

Show Notes: Ben Furman and Deborah Gorth MD, PhD

Cover Art and Infographic: Deborah Gorth MD, PhD and Meryl Gorth RD, MPH

Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Sai Achi MD, MBA, FACP

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Jordana Cohen MD, MSCE

Disclosures

Dr. Jordana Cohen and The Curbsiders report no relevant financial disclosures.

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#473 Rapid Response Series: Narrow Complex Tachyarrhythmias with Dr. Noble Maleque

Mon, 03 Mar 2025

Intro

Case 1, part 1: Unstable narrow tachyarrhythmias

Case 1, part 2: Stable, narrow tachyarrhythmias – regular rhythm

Vagal tone: Valsalva, Modified Valsalva, or Carotid Massage?

Adenosine

2nd line AV nodal blockade: metoprolol, diltiazem

Case 2: Stable, narrow tachyarrhythmias – irregular rhythm

AV nodal blockade

Amiodarone and diltiazem

Rapid fire questions/Picks of the Week

Outro

Credits

Please consolidate if performing multiple jobs (e.g. Written and Produced by: Cyrus Askin MD; cover art and infographic by Kate Grant)

Producer, writer, Infographic, cover art, and show notes by: Caroline Coleman, MD

Hosts: Meredith Trubitt, MD and Monee Amin, MD

Reviewer: Rahul Ganatra, MD MPH

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Noble Maleque, MD

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#472 DIGEST: cfDNA & cancer in Pregnancy, Vitamin K2 for Leg Cramps, PRN anti-hypertensives, GLP-1 Agonists for AUD, Short-Course Antibiotics

Mon, 24 Feb 2025

Join us as we review recent articles and news featured in The DIGEST issues #59-61, including cfDNA and incidental detection of cancer in pregnancy, vitamin K2 for nocturnal leg cramps, the danger of as-needed anti-hypertensive medications in the hospital, GLP-1 agonists for alcohol use disorder, short-course (7 vs 14 days) antibiotics for bacteremia, and patient-collected HPV testing for cervical cancer screening. Fill your brain hole with a fully digestible meal! Featuring Laura Glick MD, Nora Taranto (@norataranto), Paul Williams (@paulnwilliamz), and Matt Watto (@doctorwatto).

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Show Segments

00:00 Introduction and Overview

02:57 The IDENTIFY study: Non-Invasive Prenatal Testing and Cancer Detection with cfDNA

05:54 Implications of Non-Reportable Results in Prenatal Testing

08:51 Vitamin K2: A New Approach to Managing Nocturnal Leg Cramps

12:07 Practicality and Future of Vitamin K2 in Clinical Practice

23:21 The Dangers of As-Needed Antihypertensives in the hospital

32:21 Exploring GLP-1 Agonists for Alcohol Use Disorder

40:24 Shorter Antibiotic Courses in Sepsis

46:09 Advancements in Patient-Collected HPV Screening for cervical cancer

Credits

Written and Produced by: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Notes: Nora Taranto MD

Cover Art: Matthew Watto MD, FACP

Hosts: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Emi Okamoto MD

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Disclosures

The Curbsiders report no relevant financial disclosures.

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#471 Iron Deficiency Anemia with Dr. Tom DeLoughery

Mon, 17 Feb 2025

Intro

Rapid fire questions/Picks of the Week

Case

History and Physical

Laboratory Findings

Management of Iron Deficiency Anemia

Diet

Oral Supplementation

Unexplained Iron Deficiency

Case 2

IV Iron Supplementation

IV iron reactions

Case 3

Laboratory Follow Up Post Supplementation

When to Refer to a Hematology/Oncology specialist?

Outro

Credits

Producer,Writer, Show Notes, Cover Art, and Infographics: Sai S Achi MD MBA FACP

Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Leah Witt, MD

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Dr. Tom DeLoughery MD, MACP, FAWM

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#470 Thyroid Nodules and Thyroid Cancer for Primary Care

Mon, 10 Feb 2025

Management and Ongoing Monitoring of Thyroid Neoplasms

Join us as we dive deep into the approach for thyroid nodules with our two fantastic guests, Dr. Kaniksha Desai (Stanford Medicine) and Dr. Ana Chindris (Mayo Clinic)! Learn how to stratify these nodules for cancer risk and walk alongside our patients during treatment for thyroid cancer.

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Show Segments

Intro, guest bios

Case From Kashlak

Thyroid nodule evaluation and management

Thyroid cancer diagnosis and treatment

GLP-1s relationship to thyroid nodules and cancer

Outro

Credits

Writer, producer, show notes, infographic, cover art: Alise Burke, MD

Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP

Reviewer: Emi Okamoto MD

Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Technical Production: PodPaste

Guest: Kaniksha Desai MD and Ana Chindris MD

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